<strong>神经病理性疼痛动物模型的制备与评价方法</strong>

神经药理学报

神经病理性疼痛动物模型的制备与评价方法

武亚茹，常可欣，贾庆忠

河北医科大学，石家庄，050017，中国

出版日期:2017-10-26发布日期:2017-12-01
通讯作者:贾庆忠，男，教授，硕士生导师；研究方向：神经药理学；Tel：+86-0311-86265644，E-mail：qizhjia2000@sina.com
作者简介:武亚茹，女，硕士研究生；研究方向：神经药理学；E-mail：15369312998@163.com
基金资助:
国家自然科学基金资助项目（No.30970659），河北省高层次人才项目（No.2014038）

The Establishment and Evaluation of Animal Models of Neuropathic Pain

WU Ya-ru，CHANG Ke-xin，JIA Qing-zhong

Hebei Medical University，Shijiazhuang，050017，China

Online:2017-10-26Published:2017-12-01
Contact:贾庆忠，男，教授，硕士生导师；研究方向：神经药理学；Tel：+86-0311-86265644，E-mail：qizhjia2000@sina.com
About author:武亚茹，女，硕士研究生；研究方向：神经药理学；E-mail：15369312998@163.com
Supported by:
国家自然科学基金资助项目（No.30970659），河北省高层次人才项目（No.2014038）

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摘要/Abstract

摘要：神经病理性疼痛是由于躯体感觉系统的损伤或疾病所导致的疼痛。该文综述了外周神经损伤或带状疱疹、糖尿病、癌症等疾病所致的神经病理性疼痛动物模型及行为学评价方法。

关键词:神经病理性疼痛,动物模型,痛觉超敏,痛觉过敏

Abstract:Neuropathic pain can be defined as “pain arising as a direct consequence of a lesion or disease affecting the somato-sensory system”. This article reviews animal models of neuropathic pain induced by peripheral nerve injury，herpes zoster，diabetes and cancer and its evaluation methods.

Key words:neuropathic pain,animal model,allodynia,hyperalgesia

中图分类号:

R965

引用本文

武亚茹，常可欣，贾庆忠.神经病理性疼痛动物模型的制备与评价方法[J]. 神经药理学报,DOI: 10.3969/j.issn.2095-1396.2017.05.003.

WU Ya-ru，CHANG Ke-xin，JIA Qing-zhong.The Establishment and Evaluation of Animal Models of Neuropathic Pain[J]. Acta Neuropharmacologica,DOI: 10.3969/j.issn.2095-1396.2017.05.003.

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