张楠，张丹参
出版日期:2017-12-26发布日期:2017-12-01通讯作者:张丹参，女，教授，博士生导师；研究方向：神经药理学；Tel：+86-0313-4029188，E-mail：zhangds2011@126.com作者简介:张楠，女，硕士研究生；研究方向：神经药理学；E-mail：15733107933@163.com基金资助:
ZHANG Nan，ZHANG Dan-shen
Online:2017-12-26Published:2017-12-01Contact:张丹参，女，教授，博士生导师；研究方向：神经药理学；Tel：+86-0313-4029188，E-mail：zhangds2011@126.comAbout author:张楠，女，硕士研究生；研究方向：神经药理学；E-mail：15733107933@163.comSupported by:
摘要：
蛇床子素是伞形科植物蛇床子的主要活性成分，许多临床和现代药理实验研究表明，蛇床子素具有抗高血压，抗心律失常，抗肿瘤，抗诱变以及减缓神经退行性疾病进展的功效。另外蛇床子素对多种癌症均具有一定的抵抗作用，如：神经胶质癌、乳腺癌、胰腺癌、肺癌、胃癌等。然而蛇床子素作为一种香豆素类化合物，具有口服吸收差，生物利用度低等缺点，为改善其缺点，需要制备蛇床子素的新剂型，如，脂质体、胶束、固体分散体等，以获得更好的临床效果。该文归纳总结了近几年来蛇床子素治疗癌症的药理作用及其剂型研究，希望能为以后的研究提供帮助。
中图分类号:
张楠，张丹参.蛇床子素抗癌作用及其剂型研究进展[J]. 神经药理学报,DOI: 10.3969/j.issn.2095-1396.2017.06.004.
ZHANG Nan，ZHANG Dan-shen.Research Progress on Anticancer Effects and Dosage Forms of Osthole[J]. Acta Neuropharmacologica,DOI: 10.3969/j.issn.2095-1396.2017.06.004.
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