神经药理学报

神经药理学报››2015,Vol. 5››Issue (6): 35-39.

• 专题论著 •上一篇下一篇

中药制剂防治术后认知功能障碍的研究进展

杨晓楠, 王新生

  1. 欧宝平台登录 ，张家口，075000，中国
  • 出版日期:2015-12-26发布日期:2016-03-03
  • 通讯作者:王新生，男，教授，硕士生导师；研究方向：麻醉药物对脑认知的影响；E-mail：wxinsheng1968@sina.com
  • 基金资助:

    欧宝平台登录 自然欧宝娱乐-意甲尤文图斯亚洲区域合作伙伴 计划项目（No.120176）

Research Progress of Treatment and Protection of POCD by Traditional Chinese Medicine Preparation

YANG Xiao-Nan, WANG Xin-Sheng

  1. Hebei North University，Zhangjiakou，075000，China
  • Online:2015-12-26Published:2016-03-03
  • Contact:王新生，男，教授，硕士生导师；研究方向：麻醉药物对脑认知的影响；E-mail：wxinsheng1968@sina.com
  • Supported by:

    欧宝平台登录 自然欧宝娱乐-意甲尤文图斯亚洲区域合作伙伴 计划项目（No.120176）

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摘要：随着人口老龄化和医疗技术的进步，接受手术治疗的老年患者增多，术后认知功能障碍（postoperative cognitive dysfunction, POCD）发病率升高。深入研究POCD的发生机制以及防治措施，无论在医学层面，还是社会角度以及经济利益等方面都具有重要的意义。许多研究显示：一些中药制剂可通过改善脑部血液循环，降低脑损伤后的炎症反应，调节脑内神经递质分泌等因素，保护神经元，改善大脑的学习记忆功能，提示中药制剂可能对POCD 的预防治疗具有重要意义。

关键词:术后认知功能障碍,中药制剂,神经元保护,老年患者

Abstract:With the aging of population and the progress of medical technology, elderly patients who accept surgical treatment increase and the incidence of postoperative cognitive dysfunction (POCD) increase. Both in the medical level and social level and economic level, to research the occurrence mechanism and protection and treatment of POCD is of great significance. Many research show that some traditional Chinese medicine preparations can protect neuron and improve learning and memory ability of the brain through improving blood circulation of the brain and reducing inflammation after brain injury and adjusting the neurotransmitter in the brain secretion. Those indicate that traditional Chinese medicine preparation maybe a great significance for protection and treatment of POCD.

Key words:Postoperative cognitive dysfunction,traditional Chinese medicine preparation,Neuron protection,elderly patient

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