郝军荣,张丹参,巩跃文
出版日期:
2017-12-26发布日期:
2017-12-01通讯作者:
巩跃文,男,教授;研究方向:肝纤维化、肝衰竭机理的研究;E-mail:yuewen.gong@umanitoba.ca作者简介:
郝军荣,女,讲师;研究方向:神经药理学及相关药物;Tel:+86-0313-4029305,E-mail:haojunrong3@163.comHAO Jun-rong,ZHANG Dan-shen,GONG Yue-wen
Online:
2017-12-26Published:
2017-12-01Contact:
巩跃文,男,教授;研究方向:肝纤维化、肝衰竭机理的研究;E-mail:yuewen.gong@umanitoba.caAbout author:
郝军荣,女,讲师;研究方向:神经药理学及相关药物;Tel:+86-0313-4029305,E-mail:haojunrong3@163.com摘要:
自噬在疾病中常被描述为一把双刃剑。激活自噬或抑制自噬在创新治疗中得到广泛的应用。现在研究发现,一些骨形成蛋白(bone morphogenetic proteins,BMPs)是某些人类疾病的致病因素,而另一些与某些疾病有密切联系。自噬与BMPs 在同一疾病(如神经退行性变)中的表达是否存在一定的相关性还有待研究。在这篇综述中,我们分别概述了不同条件下的自噬的表达情况和相同条件下的BMPs 的表达,以期发现自噬与BMPs 表达之间的一些联系。自噬与BMPs 的信号通路中存在一定相关性。
中图分类号:
郝军荣,张丹参,巩跃文.自噬与骨形成蛋白在疾病中的关系[J]. 神经药理学报,DOI: 10.3969/j.issn.2095-1396.2017.06.007.
HAO Jun-rong,ZHANG Dan-shen,GONG Yue-wen.Autophagy and Bone Mmorphogenetic Proteins in Diseases and Their Relationship[J]. Acta Neuropharmacologica,DOI: 10.3969/j.issn.2095-1396.2017.06.007.
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