1. Lipton RB, Gobel H, Einhaupl KM, Wilks K, Mauskop A. Petasites hybridus root (butterbur) is an effective preventive treatment for migraine [J]. Neurology, 2004, 63(12):2240-4. 2. Silja Horak, Alexandra Koschak, Herman Stuppner, Jorg Striessnig. Use-dependent block of voltage-gated Cav2.1 Ca2+ channels by petasins and eudesmol isomers [J]. J Pharmacol Exp Ther, 2009, 330(1):220-6 3. Kan SF, Yu CH, Wu CI, Wang PS. Mechanism of S-petasin-induced apoptosis in androgen-independent prostate cancer cells [J]. Biology of Reproduction, 2005:128 4. Peter Houghton, Rui Fang, Isariya Techatanawat ,et al. The sulphorhodamine (SRB) assay and other approaches to testing plant extracts and derived compounds for activities related to reputed anticancer activity [J]. Methods, 2007, 42(4):377-87 5. Huang Dongming, Shen Yaching, Wu Chi, Huang Yaoting, Kung Fanlu, Teng Cheming,et al.Investigation of extrinsic and intrinsic apoptosis pathways of new clerodane diterpenoids in human prostate cancer PC-3 cells [J]. Eur J Pharmacol, 2004, 503(1-3):17-24 6. Molinari M. Cell cycle checkpoints and their inactivation in human cancer [J]. Cell Prolif, 2000, 33(5):261-74 7. Andrew W.Murray. Recycling the cell cycle: cyclins revisited [J]. Cell, 2004,116(2):221-34 8. Richard J Bold , Paula M Termuhlen , David J McConkey . Apoptosis, cancer and cancer therapy [J]. Surg Oncol, 1997, 6(3):133-42 9. Lara Maria Pasetto, Mario Rosario D'Andrea, Alba Ariela Brandes, Elena Rossi, Silvio Monfardini. The development of platinum compounds and their possible combination [J]. Crit Rev Oncol Hemat, 2006, 60(1):59-75 10.Jeremy L. Yap, Shilpa Worlikar, Alexander D.MacKerell,Paul Shapiro, Steven Fletcher. Small-molecule inhibitors of the ERK signaling pathway: Towards novel anticancer therapeutics [J]. ChemMedChem, 2011, 6(1):38-48 11. McCubrey JA, Chang F, Steelman LS, Lee JT, Shelton JG, Navolanic PM,et al. Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention [J]. Leukemia, 2003, 17(7):1263-93 12. John Lyons, Neil Thompson. Recent progress in targeting the Raf/MEK/ERK pathway with inhibitors in cancer drug discovery [J]. Curr Opin Pharmacol, 2005, 5(4):350-6 13. Roberts PJ, Der CJ. Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer [J]. Oncogene, 2007, 26(22):3291-310 |