神经药理学报

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蛇床子现代药理学作用及临床应用的研究进展

宋宜蕾,侯雪芹,郝吉福

  1. 山东第一医科大学,山东省医学科学院,泰安, 271016, 中国
  • 出版日期:2019-12-26发布日期:2020-03-03
  • 通讯作者:郝吉福,教授,硕士生导师;研究方向:药物新剂型与新技术; E-mail:15864769568@163.com
  • 作者简介:宋宜蕾,女,药剂学硕士研究生; E-mail:15621339326@163.com
  • 基金资助:
    国家自然科学基金项目(No.81703901),山东省重点研究项目(No.2019GSF108069),山东省中医药管理局项目(No.2019-0361)

Advances in Research on Modern Pharmacological Effects and Clinical Application of Cnidium

SONG Yi-lei,HOU Xue-qin,HAO Ji-fu

  1. Shandong First Medical University & Shandong Academy of Medical Sciences,Taian,271016,China
  • Online:2019-12-26Published:2020-03-03
  • Contact:郝吉福,教授,硕士生导师;研究方向:药物新剂型与新技术; E-mail:15864769568@163.com
  • About author:宋宜蕾,女,药剂学硕士研究生; E-mail:15621339326@163.com
  • Supported by:
    国家自然科学基金项目(No.81703901),山东省重点研究项目(No.2019GSF108069),山东省中医药管理局项目(No.2019-0361)

摘要:

蛇床子是伞形科植物蛇床的干燥成熟果实,是一种传统的中药材,在古代史书中均有对其的记载,临床 上主要以外用为主,多用于治疗妇科,外科,皮肤科等疾病。 蛇床子含有多种化学成分,主要含有香豆素类,挥发 油类,糖类以及多种微量元素。 蛇床子素是蛇床子发挥药效的主要成分之一,现代药理学研究发现,蛇床子素在 心脑血管系统,中枢神经系统,内分泌系统,免疫系统等方面的疾病均有具有的治疗效果。

关键词:蛇床子,化学成分,蛇床子素,药理作用,机制

Abstract:

Cnidium is a dry and mature fruit of the genus Umbelliferae. It is a traditional Chinese medicinal material. It has been recorded in ancient history books. It is mainly used in clinical practice and is mainly used for the treatment on gynecology and surgery. For diseases such as dermatology,male diseases are mainly based on internal medicine. Cnidium contains a variety of chemical components,mainly containing coumarins,volatile oils,sugars and various trace elements. Osthole is one of the main components of the effect of Cnidium. Modern pharmacological studies have found that osthole has therapeutic effects on diseases such as cardiovascular and cerebrovascular system,central nervous system,endocrine system and immune system.

Key words:cnidium,chemical composition,osthole,pharmacological action,mechanism

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