神经药理学报››2012,Vol. 2››Issue (2): 48-57.
李欣1, 霍玉书1,2
出版日期:
2012-04-26发布日期:
2013-11-01通讯作者:
霍玉书,教授,吉林省中科生物工程有限公司顾问,Adjunct Professor;研究方向:蛋白质药物药理学;E-mail:yushuh@hotmail.com作者简介:
李欣,女,硕士;研究方向:干细胞研究;E-mail:lixin-hd@163.comLI Xin1, HUO Yu-shu1,2
Online:
2012-04-26Published:
2013-11-01Contact:
霍玉书,教授,吉林省中科生物工程有限公司顾问,Adjunct Professor;研究方向:蛋白质药物药理学;E-mail:yushuh@hotmail.comAbout author:
李欣,女,硕士;研究方向:干细胞研究;E-mail:lixin-hd@163.com摘要:神经干细胞(neural stem cells,NSCs)是具有高度自我更新能力、能分化为神经元及胶质细胞的前体细胞。NSCs增殖及分化调控机制的研究对于其治疗神经系统退行性疾病及功能修复具有重大意义。研究表明:神经干细胞的治疗作用包括干细胞的归可巢,定植和激活自体神经干细胞,但更重要的是神经干细胞所分泌的神经细胞调控因子群(neurocyte growth regulatory factors, NGRFs)的药理学作用。深入研究这些因子不但对神经细胞再生及功能重建有重要意义,而且为研究这些因子的药理作用机理及开发大分子新药具有指导意义。
中图分类号:
李欣,霍玉书.神经干细胞与神经药理学[J]. 神经药理学报, 2012, 2(2): 48-57.
LI Xin, HUO Yu-shu.Neural Stem Cells with It’s Pharmacology[J]. Acta Neuropharmacologica, 2012, 2(2): 48-57.
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