Acta Neuropharmacologica››2017,Vol. 7››Issue (4): 1-7.DOI:10.3969/j.issn.2095-1396.2017.04.001
YANG Jie,LIU Fu-jia,TIAN Zi-xia,WANG Le-le,XIE Xin-mei,PANG Xiao-bin
Online:
2017-08-26Published:
2017-12-01Contact:
谢欣梅,女,副教授;研究方向:神经药理学;Tel/Fax:+86-0371-23880680,E-mail:xxm0475@163.com 庞晓斌,男,教授,博士生导师;研究方向:神经药理学;Tel/Fax:+86-0371-23880680,E-mail:hndxpxb@163.comAbout author:
杨杰,女,硕士研究生;研究方向:神经药理学;Tel:+86-0371-23880680,E-mail:yangjiecui@163.comSupported by:
国家自然科学基金项目(No. 81541072)
CLC Number:
YANG Jie,LIU Fu-jia,TIAN Zi-xia,WANG Le-le,XIE Xin-mei,PANG Xiao-bin.Neuroprotective Effect of Mailuoning on MCAO Rats and Its Antioxidant Mechanism[J]. Acta Neuropharmacologica, 2017, 7(4): 1-7.
[1] 江建忠,王倩,顾沿泊,等.中医治疗缺血性脑卒中研究现状与趋势系统综述[J].实用中医内科杂志,2015,29(07):4-7. [2] Qian G, Yin Yu-cheng, Pan Q G, et al. Relationship between protective effect of resveratrol on cerebral ischemia-reperfusion injury and autophagy[J]. Chinese Pharmacological Bulletin, 2013, 29(7):995-998. [3] 吴婷,张军,储继红,等.脉络宁注射液药理及药代学研究进展[J].江苏中医药,2011,43(9):93-94. [4] 杜洋.银杏达莫注射液与脉络宁治疗急性脑梗死的临床效果观察[J].临床合理用药杂志,2017,10(14):40-41. [5] 李军凯,杨高潮,黄河.脉络宁对大鼠肢体缺血再灌注损伤的保护作用[J].中西医结合心脑血管病杂志,2012,10(10):1232-1233. [6] Yang Wei-min, Shi Zi-long, Zhang Shi-hong, et al. Mailuoning for acute ischaemic stroke[J]. Cochrane Database Syst Rev. 2015, 6(9):CD007028. [7] 蔡松泉,蔡宇.脑心通和脉络宁在脑梗死治疗中的应用价值[J].中国药物经济学,2017,12(10):43-45. [8] Wang Dai-jun, Tian Hua. Effect of Mailuoning injection on 8-iso-prostaglandin F2 alpha and superoxide dismutase in rabbits with extremity ischemia-reperfusion injury[J]. Journal of Surgical Research, 2014, 192(2):464-70. [9] 冯有为,林红伍,李文吟,等.脉络宁注射液预防和治疗血栓性疾病作用机理的探讨和临床观察[J].西部中医药,2000(3):16-17. [10] Cui Li-li, Zhang Xiang-jian, Yang Rui, et al. Baicalein is neuroprotective in rat MCAO model: Role of 12/15-lipoxygenase, mitogen-activated protein kinase and cytosolic phospholipase A2[J]. Pharmacology Biochemistry & Behavior, 2010, 96(4):469-475. [11] Longa E Z, Weinstein P R, Carlson S, et al. Reversible middle cerebral artery occlusion without craniectomy in rats[J]. Stroke, 1989, 20(1):84. [12] 魏孟琳,田莉,王小琴,等.大鼠脑缺血预处理对缺血再灌注神经功能的影响[J].神经药理学报,2016,6(2):7-13. [13] Liu Xiao-bai, Wang Zhen-hua, Wang Ping, et al. Green tea polyphenols alleviate early BBB damage during experimental focal cerebral ischemia through regulating tight junctions and PKCalpha signaling[J]. Bmc Complementary & Alternative Medicine, 2013, 13(1):187. [14] Kimmo T Jokivarsi, Timo Liimatainen, Risto A Kauppinen, et al. Relaxation along a fictitious field (RAFF) and Z-spectroscopy using alternating-phase irradiation (ZAPI) in permanent focal cerebral ischemia in rat[J]. PLoS One, 2013, 8(7):e69157. [15] 李洪亮,薛智慧,龙抗胜,等.线栓法制备MCAO模型大鼠的经验体会[J].中国中医急症,2014,23(12):2216-2219. [16] 郑延泽,田彩云,张浩楠,等.大鼠脑缺血不同时相神经功能评分、脑梗死灶体积、血清神经元特异性烯醇化酶含量的变化[J].神经药理学报,2014,4(03):17-21. [17] Jorge G Farías, Victor M Molina, Rodrigo A Carrasco, et al. Antioxidant therapeutic strategies for cardiovascular conditions associated with oxidative stress[J]. Nutrients, 2017, 9(9):966. [18] Demetrios Moris, Michael Spartalis, Eleni Tzatzaki, et al. The role of reactive oxygen species in myocardial redox signaling and regulation[J]. Annals of Translational Medicine, 2017, 5(16):324. [19] Zuluaga M, Gueguen V, Letourneur D, et al. Astaxanthin-antioxidant impact on excessive reactive oxygen species generation induced by ischemia and reperfusion injury[J]. Chem Biol Interact, 2017, 279(24):145-158. [20] Ma Xu-dong, Song Jin-ning, Zhang Ming, et al. Advances in research of the neuroprotective mechanisms of cerebral ischemic postconditioning[J]. International J Neuroscience, 2014, 125(3):161-169. [21] 王欢欢,薛茜,邹玉安.内源性抗氧化应激机制在缺血预处理与缺血再灌注损伤中的研究进展[J].神经药理学报,2016,6(2):46-52. [22] Thomas H Sanderson, Christian A Reynolds, Rita Kumar, et al. Molecular mechanisms of ischemia-reperfusion injury in brain: pivotal;role of the mitochondrial membrane potential in reactive oxygen species;generation[J]. Molecular Neurobiology, 2013, 47(1):9. [23] Neil Granger D, Peter R Kvietys. Reperfusion injury and reactive oxygen species: The evolution of a concept[J]. Redox Biology, 2015, 11(6):524-551. [24] Stefan Dröse, Anna Stepanova, Alexander Galkin. Ischemic A/D transition of mitochondrial complex I and its role in ROS generation[J]. Biochimica et Biophysica Acta, 2016, 1857(7):946. [25] Brent R Stockwell, Jose Pedro Friedmann Angeli, Hulya Bayir, et al. Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease[J]. Cell, 2017, 171(2):273. [26] 闫文凤,杨志明.氧化应激与心肌细胞缺血再灌注损伤[J].中国心血管病研究,2016,14(9):769-772. [27] Xiao-Qin Hu, Wang Z R, Zhang C Q, et al. The effect of resveratrol against atrial oxidative stress injury induced by rapid-pacing in isolated rabbit hearts[J]. Chinese J Cardiac Pacing & Electrophysiology, 2014,28(1):50-54. [28] Dong Liang, He Yong-zhi, Wang Yuan-liang, et al. Research progress on application of superoxide dismutase (SOD)[J]. J Agricultural Science & Technology, 2013, 15(5):53-58. [29] Liu Wei, Xu Zhao-fa, Deng Yu, et al. Protective effects of memantine against methylmercury-induced glutamate dyshomeostasis and oxidative stress in rat cerebral cortex[J].Neurotoxicity Research, 2013, 24(3):320-37. [30] 颜娟,郑茂东,崔玉环,等.大黄酚脂质体对脑缺血再灌注损伤小鼠动态抗氧化作用研究[J].神经药理学报,2016,6(1):9-17. [31] 张婧,邹玉安,董晓华.缺血预处理对脑缺血再灌注损伤保护作用的研究进展[J].神经药理学报,2015,5(5):57-64. [32] 彭智远,刘旺华,曹雯.脑缺血再灌注损伤细胞凋亡机制的研究进展[J].中华中医药学刊,2017,35(08):1957-1961. [33] Obulesu M, M Jhansi Lakshmi. Apoptosis in Alzheimer's disease: an understanding of the physiology, pathology and therapeutic avenues[J]. Neurochemical Research, 2014, 39(12):2301-2312. [34] 尹智勇,杨俊元,祁宏.Bcl-2蛋白质家族调控细胞凋亡机制的研究进展[J].信阳师范学院学报:自然科学版,2017,30(2):340-344. [35] Xuan Liu, Zhu Xiang-yang, Miao Chen, et al. Resveratrol protects PC12 cells against OGD/R-induced apoptosis via the mitochondrial-mediated signaling pathway[J].生物化学与生物物理学报(英文), 2016, 48(4):342. [36] 李敏,林俊.细胞凋亡途径及其机制[J].国际妇产科学杂志,2014,41(02):103-107. [37] 任丽平,李先佳,金少举.基于caspase-3/bcl-2/bax信号通路的槐定碱诱导胰腺癌细胞株capan-1凋亡机制研究[J].中国现代应用药学,2017,34(03):325-328. |
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