ACTA NEUROPHARMACOLOGICA››2020,Vol. 10››Issue (4): 51-57.DOI:10.3969/j.issn.2095-1396.2020.04.009
Previous ArticlesNext Articles
ZHANG Si-qi,ZHANG Yuan-yuan
Online:
2020-08-26Published:
2020-08-26About author:
张元元,讲师,博士;研究方向:眼科疾病及抗肿瘤药物筛选;E-mail:yuanyuanzhangyyz@163.comSupported by:
CLC Number:
ZHANG Si-qi, ZHANG Yuan-yuan. Exosomes Derived from Retinal Pigment Epithelial Cells and Age-Related Macular Degeneration[J]. ACTA NEUROPHARMACOLOGICA, 2020, 10(4): 51-57.
[1] 晓琴, 鲁占军, 张天资, 等. 年龄相关性黄斑变性危险因素研究进展[J]. 中国老年学杂志, 2019, 39(19): 4863-4866. [2] 徐梦乔, 孙晓东.外泌体与年龄相关性黄斑病变的研究进展[J]. 中华眼科杂志, 2017, 53(10): 786-790. [3] Johnstone R M, Adam M, Hammond J R,et al.Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes)[J]. J Biological Chemistry, 1987, 262(19):9412-9420. [4] Fitzner Dirk, Schnaars Mareike, Van Rossum Denise,et al.Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis[J]. J Cell Ence, 2011, 124(Pt 3):447-458. [5] Joanna Kowal, Mercedes Tkach, Clotilde Théry.Biogenesis and secretion of exosomes[J]. Current Opinion in Cell Biology, 2014, 29:116-125. [6] 杨婧, 陈松.外泌体在年龄相关性黄斑变性发病机制中的作用研究进展[J]. 中华实验眼科杂志, 2017, (1):83-86. [7] Priyatham S Mettu, Albert R Wielgus, Sally S Ong,et al.Retinal pigment epithelium response to oxidant injury in the pathogenesis of early age-related macular degeneration[J]. Molecular Aspects of Medicine, 2012, 33(4):376-398. [8] Wang Hai-bo, Han Xiao-kun, Erika S Wittchen,et al.TNF-α mediates choroidal neovascularization by upregulating VEGF expression in RPE through ROS-dependent β-catenin activation[J]. Molecular Vision, 2016, 22:116-128. [9] Wang Ai-ling, Thomas J Lukas, Yuan Ming,et al.Autophagy, exosomes and drusen formation in age-related macular degeneration[J]. Autophagy, 2009, 5(4):563-564. [10] Parameswaran G Sreekumar, Ram Kannan, Mizuki Kitamura,et al.αB Crystallin is apically secreted within exosomes by polarized human retinal pigment epithelium and provides neuroprotection to adjacent cells[J].PloS One, 2010, 5(10):e12578. [11] Suraj P Bhat, Rajendra K Gangalum.Secretion of αB-Crystallin via exosomes: New clues to the function of human retinal pigment epithelium[J]. Communicative & Integrative Biology, 2011, 4:6(6):739-741. [12] Juan E Grunwald, Tatyana I Metelitsina, Joan C Dupont,et al.Reduced foveolar choroidal blood flow in eyes with increasing AMD severity[J]. Investigative Ophthalmology & Visual Science, 2005, 46(3):1033-1038. [13] Marcella Nebbioso, Alessandro Lambiase, Alberto Cerini,et al.Therapeutic approaches with intravitreal injections in geographic atrophy secondary to age-related macular degeneration: current drugs and potential molecules[J]. International J Molecular Sciences, 2019, 20(7):1693. [14] Cheung L K, Eaton A.Age-related macular degeneration[J]. Pharmacotherapy the J Human Pharmacology & Drug Therapy, 2013, 33(8):838-855. [15] Lucia Biasutto, Antonella Chiechi, Robin Couch,et al.Retinal pigment epithelium (RPE) exosomes contain signaling phosphoproteins affected by oxidative stress[J]. Experimental Cell Research, 2013, 319(13):2113-2123. [16] 欧阳灵艺, 邢怡桥. 抗VEGF药物在湿性年龄相关性黄斑变性中的应用进展[J]. 国际眼科杂志, 2020, 20(1):74-78. [17] 张惟, 杨婧, 陈松, 等. 氧化应激下视网膜色素上皮细胞外泌体对视网膜色素上皮细胞血管内皮生长因子A及丝氨酸/苏氨酸激酶表达的影响[J]. 中华眼底病杂志, 2017, 33(1):57-61. [18] 俞永珍, 邹秀兰, 邹玉平. 氧化应激及抗氧化物在年龄相关性黄斑变性中的作用[J]. 眼科新进展, 2015, 035(005):489-492. [19] 许斐平, 汪枫桦, 孙晓东. 内质网应激在年龄相关性黄斑变性中的作用[J]. 中华实验眼科杂志, 2012, 30(11): 1052-1056. [20] 徐莹, 孙晓东.干性年龄相关性黄斑变性患者视网膜色素上皮细胞损伤机制[J]. 眼科新进展, 2011, 31(7): 98-100, 103. [21] Chen Hui-yi, Liu Bin, Thomas J Lukas,et al.The aged retinal pigment epithelium/choroid: a potential substratum for the pathogenesis of age-related macular degeneration[J]. PloS One, 2008, 3(6): e2339. [22] Katayoon Baradaran Ebrahimi, Natalia F Callaway, Marisol Cano,et al.Oxidized low-density-lipoprotein-induced injury in retinal pigment epithelium alters expression of the membrane complement regulatory factors CD46 and CD59 through exosomal and apoptotic bleb release[J]. Advances in Experimental Medicine & Biology, 2014, 801(6):259. [23] Ai Ling Wang, Thomas J Lukas, Ming Yuan,et al.Autophagy and exosomes in the aged retinal pigment epithelium: possible relevance to drusen formation and age-related macular degeneration[J]. PloS One, 2009, 4(1):e4160. [24] 黄叔仁. 老年性黄斑变性[J]. 实用眼科杂志, 1992, (7): 10-13. [25] 卢怡洁, 秦珊, 秦波.诱导多能干细胞治疗年龄相关性黄斑变性的研究进展[J]. 国际眼科杂志, 2019, 19(10): 1692-1695. [26] 阮熵, 汪枫桦.干细胞定向分化视网膜色素上皮治疗年龄相关性黄斑变性的研究进展[J]. 上海交通大学学报: 医学版, 2018, 38(09):140-145. [27] 刘明, 夏晓丽, 方攀峰. 视网膜色素上皮细胞移植治疗年龄相关性黄斑变性的临床研究及相关药物开发[J]. 药学进展, 2019, (6): 430-436. |
No related articles found! |
Viewed | ||||||
Full text |
|
|||||
Abstract |
|
|||||