ACTA NEUROPHARMACOLOGICA››2011,Vol. 1››Issue (4): 55-64.

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Research Advances in Using Ginseng to Prevent and Treat Parkinson’s Disease

LI Dong-wei,DOU De-qiang

  1. Liaoning University of Traditional Chinese Medicine,Dalian,116600,China
  • Online:2011-08-26Published:2012-11-24

Abstract:The current research in Parkinson’s disease and progress in using of ginseng to treat Parkinson’s disease,and mechanisms of ginsenosides-induced protection of dopaminergic neurons in substantia nigra were reviewed,which lay a foundation for the reasonable application of ginseng in the treatment of Parkinson’s disease. Ginsenosides can play an important role in protecting dopaminergic neurons by countering oxidative stress,inhibiting Ca2+channel and blocking the signaling pathways of neurons apoptosis.

Key words:PD,ginseng,ginsenoside,dopamine(DA),neuroprotective effects

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