Acta Neuropharmacologica››2013,Vol. 3››Issue (1): 37-47.

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Effect of Sleep on Memory Consolidation

SHENG Zhao-fu, ZHANG Yong-he

  1. Department of Pharmacology, School of Basic Medical Science, Peking University, Bejing, 100191, China
  • Online:2013-02-26Published:2014-06-27
  • Contact:张永鹤,男,教授,博士生导师;研究方向:睡眠及精神神经药理;E-mail: zhyh@hsc.pku.edu.cn
  • About author:盛兆福,男,博士研究生;研究方向:睡眠及精神神经药理;E-mail:jianbingxuan@163.com
  • Supported by:

    国家自然科学基金项目(No:81173031)

Abstract:Delayed post learning sleep but not wakefulness enhances memory consolidation. Different types of learning have unique sleep-related memory consolidation mechanisms that act in dissociable brain regions during different sleep phases throughout the night. Sleep exerts beneficial effect on memory consolidation by improving formation of long-term potentiation. Total sleep deprivation, rapid eye movement sleep deprivation and sleep fragmentation may lead to memory deficits through different molecular mechanisms.

Key words:sleep,learning,memory,electroencephalography,long-term potentiation

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