Acta Neuropharmacologica››2014,Vol. 4››Issue (6): 55-64.

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Progress in Understanding the Mechanism of Protective Effects of Cerebral Ischemia Injury

ZHAO Wei, LI Fang-jiang, WANG Shu

  1. 1. Department of Pharmacy, Hebei North University, Zhangjiakou, 075000, Hebei, China
    2. Department of Cardiovascular Medicine, The First Affiliated Hospital, Hebei North University, Zhangjiakou, 075000, Hebei, China
  • Online:2014-12-26Published:2015-01-20
  • Contact:王树,男,副教授,硕士生导师,研究方向:心脑血管损伤研究,Tel: 86-313-4029308,E-mail:wangshu388@163.com
  • About author:赵薇,女,硕士研究生,研究方向:心脑血管损伤研究, E-mail:670734978@qq.com
  • Supported by:

    河北省科技支撑计划项目(No.07276166), 欧宝平台登录 自然欧宝娱乐-意甲尤文图斯亚洲区域合作伙伴 项目(No. 2010022)

Abstract:Cerebral ischemic disease is a common disease clinically, and frequently-occurring disease. Research shows that there is serious harm after cerebral ischemia reperfusion injury. In recent years, the cerebral ischemia reperfusion protection was laid emphasis on by the international medical circles. It is very significant for the protective mechanism of further research of cerebral ischemia injury, the discovery of cerebral ischemic disease treatment targets, and the development of the corresponding drugs. This review was focused on the research progress in understanding the mechanism of protective effects of cerebral ischemia injury.

Key words:cerebral ischemic injury,oxygen radical,inflammatory response,excitatory amino acid,apoptosis,heat stock protein,ischemical preconditioning,mild hypothermia

CLC Number:

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