Acta Neuropharmacologica››2015,Vol. 5››Issue (6): 30-34.
Previous ArticlesNext Articles
WANG Ying-ying1,2, SONG Xiu-yun1,WANG Qi2, CHEN Nai-hong1
Online:
2015-12-26Published:
2016-03-03Contact:
陈乃宏,男,博士后,研究员;研究方向:神经药理学和神经分子生物学; Tel: +86-010-63165177,E-mail: chennh@imm.ac.cnAbout author:
王莹莹,女,硕士研究生; E-mail:wangyingyingwangye@163.comSupported by:
国家自然科学基金项目(NO.81173578, 81273629, 81373997, 21272278);北京市自然科学基金项目(NO.7131013、7142115)新药作用机制研究与药效评价北京市重点实验室资助项目(BZ0150)
CLC Number:
WANG Ying-ying, SONG Xiu-yun, WANG Qi, CHEN Nai-hong.Application of Natural Antioxidants in the Progress of Alzheimer's Disease[J]. Acta Neuropharmacologica, 2015, 5(6): 30-34.
[1]段磊, 司继刚, 刘萍, 等. 阿尔茨海默病药物治疗研究进展[J]. 河北医药, 2015, 7: 1077-1080. [2]应侠,吴振,雷严,等. 阿尔茨海默病的发病机制及治疗药物研究进展[J]. 中国药房, 2014, 33:3152-3155. [3]付艳玲, 薛寿儒. 氧化应激与阿尔茨海默病以及抗氧化治疗研究进展[J]. 国际神经病学神经外科学杂志, 2010, 4: 336-340. [4]孙磊, 杨莹, 窦彩艳. 阿尔兹海默病治疗的研究进展[J]. 医学信息:中旬刊, 2010, 7: 1969-1970. [5]宋玉菲, 付剑亮. 阿尔茨海默病与氧化应激[J]. 国际神经病学神经外科学杂志, 2015, 3: 290-293. [6]Elizabeth E Devore, Francine Grodstein, Frank J A van Rooij. Dietary antioxidants and long-term risk of dementia[J].Arch Neurol, 2010, 67(7): 819–825. [7]David J Llewellyn, Iain A Lang, Kenneth M Langa, et al. Vitamin d and risk of cognitive decline in elderly persons[J]. Arch Intern Med, 2010, 170(13): 1135–1141. [8]David S Wald, Anuradhani Kasturiratne, Mark Simmonds. Effect of folic acid, with or without other B vitamins, on cognitive decline: meta-analysis of randomized trials[J]. J American Medicine, 2010, 123(6): 522–527.e2 [9]E Giraldo, A Lloret, T Fuchsberger, et al. A β and tau toxicities in Alzheimer’s are linked via oxidative stress-induced p38 activation: Protective role of vitamin E[J].Redox Biol, 2014, 2: 873–877. [10]Ana Lloret, Mari-Carmen Badía, Nancy J Mora, et al. Gender and age-dependent differences in the mitochondrial apoptogenic pathway in Alzheimer's disease[J]. Free Radic Biol Med, 2008, 44(12): 2019-2025. [11]张俏忻, 罗文鸿, 李慧, 等. 阿魏酸等五种酚类物质对DNA氧化损伤的影响[J]. 癌变.畸变.突变, 2006, 18(1): 12-15. [12]周红伟, 章军建, 熊丽. 慢性脑缺血大鼠海马PARP、MDA的表达及阿魏酸钠的抗氧化作用[J]. 中风与神经疾病志, 2005, 22(3): 213-215. [13]Antonella Sgarbossa, Daniela Giacomazza, Marta di Carlo. Ferulic acid: a hope for Alzheimer’s disease therapy from plants[J]. Nutrients. 2015 Jul 15;7(7):5764-82. [14]杨植媛, 吴红彦, 李海龙, 等. 当归含药血清对阿尔兹海默病细胞模型损伤的保护作用[J]. 辽宁中医杂志, 2014, 1: 164-167. [15] 江海涛. 灵芝、裂褶菌多糖体外抗氧化活性的实验研究[J]. 南京晓庄学院学报, 2012, 3: 41-44. [16]Moongkarndi P, Jaisupa N, Samer J, et al. Comparison of the biological activity of two different isolates from mangosteen[J].J Pharm Pharmacol, 2014, 66(8): 1171-1179. [17]杨卉. 中药提取物治疗阿尔茨海默病的研究进展[J]. 湖北中医药大学学报, 2014, 16(1): 113-115. [18]Ankica Jelenkovi? , Marina D Jovanovi? , Ivana Stevanovi? , et al. Influence of the green tea leaf extract on neurotoxicity of aluminium chloride in rats[J].Phytother Res, 2014, 28(1): 82-87. [19]于腾飞, 刘屏. 天然药物中抗氧化成分研究进展[J]. 中国中医药信息杂志, 2009, 16(7): 106-109. [20]刘晓麒, 曹恩华. 脂质过氧化引起的DNA损伤研究进展[J]. 生物化学与生物物理进展, 1994, 3: 218-222+281-282. [21]Muriel Arimon, Shuko Takeda , Kathryn L Post , et al. Oxidative stress and lipid peroxidation are upstream of amyloid pathology[J].Neurobiol Dis, 2015, pii: S0969-9961(15)00231-4. [22]Hu D, Li C, Han N, et al. Deoxyschizandrin Isolated from the Fruits of Schisandra chinensis Ameliorates Aβ 1–42 -induced Memory Impairment in Mice[J].Planta Med, 2012, 78(12): 1332-1336. [23]Sun Li-wei, Cara K Isaak, Zhou Ya-ling, et al. Salidroside and tyrosol from Rhodiola protect H9c2 cells from ischemia/reperfusion-induced apoptosis[J].Life Sci, 2012, 91(5-6):151-158. [24]张振清, 张翠红, 顾平, 等. 红景天苷对β淀粉样蛋白诱导SH-SY5Y细胞损伤的保护作用研究[J]. 中华中医药杂志, 2014, 11: 3571-3575. [25]张佳, 宋立刚, 孔卫娜, 等. 红景天苷对Aβ_(1~40)所致阿尔茨海默病模型大鼠认知功能改善作用及机制探讨[J]. 中国中药杂志, 2012, 14: 2122-2126. [26]刘刚, 王辉, 张先洲, 等. 青藤碱清除氧自由基和抗脂质过氧化作用[J]. 中草药, 2006, 37(1): 84-87. [27]刘满红, 王如阳. 植物活性多糖清除羟自由基的抗氧化性能研究[J]. 云南中医中药杂志, 2009, 30(6): 57-58. [28]赵杰,官守涛,孙设宗,等. 半枝莲多糖清除氧自由基及抗脂质过氧化作用[J]. 中成药, 2012, 34(7): 1361-1364. [29]孔令东, 杨澄, 仇熙, 等. 黄柏炮制品清除氧自由基和抗脂质过氧化作用[J]. 中国中药杂志, 2001, 26(4): 29-32. [30]Yanyan Zhou, Ning Xie, Libo Li, et al. Puerarin alleviates cognitive impairment and oxidative stress in APP/PS1 transgenic mice+Effects of Brussels Sprouts and Their Phytochemical Components on Oxidative Stress–Induced Neuronal Damages in PC12 Cells and ICR Mice[J]. J International Neuropsycho Pharmacology, 2014, 17, 635–644. [31]Lawrence M Sayre, George Perry, Peggy L R Harris, et al. In situ oxidative catalysis by neurofibrlllary tangles and senile plaques in Alzheimer’s disease: a central role for bound transition metals[J].J Neurochem, 2000, 74(1):270-279. [32]Huang Xu-dong, Craig S Atwood, Mariana A Hartshorn, et al. The Aβ peptide of Alzheimer’s disease directly produces hydrogen peroxide through metal ion reduction[J].Biochemistry, 1999, 38(24):7609-7616. [33]Marian Valko, Klaudia Jomova , Christopher J Rhodes , et al. Redox and non-redox-metal-induced formation of free radicals and their role in human disease[J].Springer-Verlag Berlin Heidelberg, 2015, 90(1):1-37. [34]汪何雅, 赵显峰, 荫士安, 等. 中药与食物成分之间的抗氧化协同作用[J]. 中华预防医学杂志, 2006, 40(3): 212-214. [35]Zhang J, Mori A, Chen Q, et al. Fermented papaya preparation attenuates β-amyloid precursor protein: β-amyloid-mediated copper neurotoxicity in β-amyloid precursor protein and β-amyloid precursor protein Swedish mutation overexpressing SH-SY5Y cells[J].Neuroscience, 2006, 143(1):63-72. [36]张琦, 郝艳兵, 张荣平, 等. 天然抗氧化剂在医药领域的研究进展[J]. 中国现代医生, 2013, 28: 22-24. [37] 陈园,仇农学,熊犍. 植酸的体内抗氧化活性研究[J]. 现代食品科学,2011,2(27):131-134. [38]刘方, 武子斌, 牛淑敏, 等. 中药材抗氧化及自由基清除活性的研究[J]. 中国药学杂志, 2001, 36(7): 12-15. [39]蒋锋. 中药抗氧化作用研究的现状与展望[J]. 贵阳中医学院学报, 1998, 3: 51-53. [40]Kenjiro Ono , Margaret M Condron , Lap Ho, et al. Effects of grape seed derived polyphenols on amyloid beta-protein self-assembly and cytotOxicity[J]. J Biol Chem, 2008, 283(47):32176-32187. [41]任晓辉, 周冠群, 李中华, 等. 治疗阿尔兹海默病的天然药物活性成分研究现状[J]. 新疆医学, 2006, 05: 268-271. [42]Haruyo Ichikawa , Wang Xue-jiang, Konishi Tetsuya. Role of component herbs in antioxidant activity of shengmai san a traditional Chinese Medicine for mulapreventing cerebral oxidative damage in rat[J]. Am J Chin Med, 2003, 31(4): 509-521. |
[1] | ZHANG Jian-mei, ZHANG Dan-shen.Advances in Research on Treatment of Ulcerative Colitis with Chinese and Western Medicine#br#[J]. ACTA NEUROPHARMACOLOGICA, 2020, 10(5): 43-47. |
[2] | ZHANG Hao-nan, YANG Hui.Recent Advances in the Research of the Protective Effect of Natural Drugs on Cerebral Ischemia-Reperfusion Injury[J]. ACTA NEUROPHARMACOLOGICA, 2020, 10(4): 14-20. |
[3] | JIN Shan, ZHANG Dan-shen.Research Progress of Lidocaine Transdermal Preparations[J]. ACTA NEUROPHARMACOLOGICA, 2020, 10(3): 16-20. |
[4] | LIN Si-mei, ZHOU Hong, YANG Bao-xue.The Relationship between Hyperuricemia and Chronic Kidney Disease[J]. ACTA NEUROPHARMACOLOGICA, 2020, 10(2): 55-64. |
[5] | ZHONG Jia-hong, WANG Hai-tao, XU Jiang-ping.Inhibition of Phosphodiesterase 4 by FCPR16 Protects SH-SY5Y Cells against MPP+-Induced Cell Death through Activating cAMP/PKA/CREB and Epac/Akt Signaling Pathways[J]. Acta Neuropharmacologica, 2018, 8(4): 54-55. |
[6] | BAI Ru-bing,ZHANG Zhong-quan,CEN Juan.The Expression of P-Glycoprotein in Neurons and the Effect of Oxidative Stress on P-Glycoprotein[J]. Acta Neuropharmacologica, 2018, 8(3): 9-. |
[7] | BIAN Fang1,HOU Yan-ning2.Research Progress of the ATP Sensitive Potassium Channels in Neurodegenerative Diseases[J]. Acta Neuropharmacologica, 2017, 7(5): 52-58. |
[8] | YANG Jie,LIU Fu-jia,TIAN Zi-xia,WANG Le-le,XIE Xin-mei,PANG Xiao-bin.Neuroprotective Effect of Mailuoning on MCAO Rats and Its Antioxidant Mechanism[J]. Acta Neuropharmacologica, 2017, 7(4): 1-7. |
[9] | Zhang Hai-wei,Zhang Li.Research Progress on Pinocembrin:Potential Therapeutic Applications and Action Mechanisms[J]. Acta Neuropharmacologica, 2016, 6(5): 45-52. |
[10] | WANG Sha-sha,ZHANG Zhao,ZHANG Mei-jin,HU Jin-feng,CHEN Nai-hong.Advances of Nrf 2/ARE Signaling Pathway in the Major Depression Disorder[J]. Acta Neuropharmacologica, 2016, 6(3): 32-37. |
[11] | QIN Xue-qing,YANG Zhi-hong,SUN Xiao-bo.A Review of Studies on Blood Brain Barrier in vitro Model[J]. Acta Neuropharmacologica, 2016, 6(1): 25-34. |
[12] | ZHANG Mei-jin,WANG Sha-sha,ZHANG Zhao,CHEN Nai-hong,HU Jin-feng.Role of Nuclear Transcription Factor Nrf2 in Parkinson’s Disease[J]. Acta Neuropharmacologica, 2016, 6(1): 35-40. |
[13] | LOU Yu-xia,ZHANG Zhao,WANG Zhen-zhen,JIANG Yi-na,ZHANG Yi,LI Lin,CHEN Nai-hong.Parkinson Associated DJ-1 Gene and Oxidative Stress[J]. Acta Neuropharmacologica, 2016, 6(1): 58-64. |
[14] | YAN Juan,ZHENG Mao-dong.Protective Effects and Mechanisms of L-carnitine in the Nervous System[J]. Acta Neuropharmacologica, 2015, 5(1): 45-50. |
[15] | ZHOU Si-bai, LI Jin-ze, LIU Rui, ZHANG Tian-tai.Recent Development of the Flavonoids on the Treatment of Alzheimer’s Disease[J]. Acta Neuropharmacologica, 2015, 5(1): 51-58. |
Viewed | ||||||
Full text |
|
|||||
Abstract |
|
|||||