Acta Neuropharmacologica››2013,Vol. 3››Issue (5): 2-12.

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An Update on Antipsychotic Drugs: New Targets and New Mechanisms

GUO Lin, ZHEN Xue-chu

  1. College of Pharmaceutical Sciences, Soochow University, Suzhou, 215123, China
  • Online:2013-10-26Published:2014-06-27
  • Contact:镇学初,男,教授,博士生导师;研究方向:神经精神药理;Tel:+86-0512-65880369,E-mail:zhenxuechu@suda.edu.cn
  • About author:郭琳,男,博士;研究方向:神经药理;Tel:+86-0512-65880369,E-mail:guolin0724@163.com

Abstract:Schizophrenia is a devastating disease affecting nearly 1% population worldwide. Since 1950s, both typical and atypical antipsychotic drugs have been introduced to treat the disease. Although great efforts and progress have been made, the challenge remains. The current paper will review the recent progress in developing novel anti-psychotic drugs and discuss the challenges and opportunities.

Key words:schizophrenia,dopamine,glutamate,5-hydroxytryptamine

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