ACTA NEUROPHARMACOLOGICA››2014,Vol. 4››Issue (5): 55-64.

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Pharmacological Actions and Therapeutic Applications of Tanshinone ⅡA

MEI Yan-fei, ZHANG Dan-shen

  1. 1 Department of Pharmancy, Hebei North University, Zhangjiakou, 075000, China 2 Hebei University Of Science and Technology, Shijiazhuang, 050018, China
  • Online:2014-10-26Published:2015-01-20
  • Contact:张丹参,女,教授,博士生导师;研究方向:神经药理学;Tel:+86-0311-81668016,E-mail:zhangds2011@126.com
  • About author:梅艳飞,女,硕士研究生;研究方向:神经药理学;E-mail:myf_1990421@163.com

Abstract:Tanshinone ⅡA, one of the mainly active ingredients from Salvia miltiorrhiza Bge, is the basis of its pharmacological activity. Tanshinone ⅡA can increase the coronary blood flow, improve the myocardial function, reduce platelet aggregation, etc, therefore it is widely used in clinical treatment of cardio-cerebral blood vessel diseases. Because tanshinone ⅡA has various biological activities, such as anti-tumor, antioxidant, anti-inflammatory and antibacterial, these actions could enlarge its range of applications. In this review, the pharmacological actions and clinical applications of tanshinone ⅡA was summarized.

Key words:tanshinone ⅡA,pharmacological actions,therapeutic applications

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