Abstract:Objective：To observe the effects of Xingnaojing injection on acute ischemic stroke patients with high-sensitivity CRP（hs-CRP），interleukin-6（IL-6） and total cholesterd（TC） level，and to explore its possible mechanism.Methods：100 patients with acute ischemic stroke were treated in department of neurology of hospital of Nanyang Nan Shi from December 2013 to October 2015. They were randomly divided into observation group and control group，50 cases in each group. Control group patients were given regular treatment，while the patients in observation group were given Xingnaojing injection based on regular treatment，once a day for 2 weeks（ one course）. Venous blood of all patients was drawn to detect the levels of hs-CRP，IL-6 and TC before
treatment and after treatment for first，3，6，14，10 days.Results：The levels of hs-CRP，IL-6 and TC in all patients showed a slow downward trend，while compared with the control group，the observation group was decreased more significantly（ P<0.05）. The neurological rehabilitation of observation group were significantly higher than control group（P<0.05）.Conclusion： Xingnaojing injection can significantly decrease the level of hs-CRP，IL-6 and TC in serum of patients with acute ischemis level，which has a neuroprotective function.

Key words:Xingnaojing injection,acute ischemic stroke,high-sensitivity CRP（hs-CRP） ,interleukin-6（IL-6）,total cholesterd（TC）