1. Thomas B, Beal MF. Parkinson's disease[J]. Hum Mol Genet, 2007, 16(02): R183-194. 2. Min Jeong Park, Sang-Myung Cheon, Hye-Ran Bae,et al.Elevated levels of α-synuclein oligomer in the cerebrospinal fluid of drug-naïve patients with Parkinson's disease[J].J Clin Neurol, 2011, 7(4):215-222. 3. Gizem Donmez, Anirudh Arun, Chee-Yeun Chung,et al. SIRT1 protects against α-synuclein aggregation by activating molecular chaperones[J]. J Neurosci, 2012, 32(1):124-132. 4. Charalambos Karakasis, Kallirhoe Kalinderi, Zoe Katsarou,et al.Association of brain-derived neurotrophic factor (BDNF) Val66Met polymorphism with Parkinson's disease in a Greek population[J].J Clin Neurosci, 2011, 18(12):1744-1745. 5. Tofaris GK, Spillantini MG. Alpha-synuclein dysfunctionin lewy body diseases[J]. Mov Disorders, 2005, 20(Suppl 12): S37-44. 6. Beyer Katrin, Ariza Aurelio. Protein aggregation mechanisms in synucleinopathies: commonalities and differences[J]. J Neuropathol Exp Neurol, 2007, 66(11): 965-974. 7. George J Siegel, Neelima B Chauhan. Neurotrophic factors in Alzheimer's and Parkinson's disease brain[J]. Brain Res Brain Res Rev, 2000, 33(2-3): 199-227. 8. Changgeng Peng, Liviu Aron, Rudiger Klein,et al. Pitx3 is a critical mediator of GDNF-induced BDNF expression in nigrostriatal dopaminergic neurons[J]. J Neurosci, 2011, 31(36):12802-12815. 9. Tamara Aid, Anna Kazantseva, Marko Piirsoo,et al. Mouse and rat BDNF gene structure and expression revisited[J]. J Neurosci Res, 2007, 85(3): 525-535. 10. Yuan Y[J]. Cell Mol Neurobiol, 2008, 28(1): 21-33.uhe, Jin Jin, Yang Bo,et al. Overexpressed alpha-synuclein regulated the nuclear factor-kappaB signal pathway 11. Chinta SJ, AndersenJK.Dopaminergic neurons[J]. Int J Biochem Cell Biol,2005, 37(5): 942-946. 12. Le Weidong, Pan Tianhong, Huang Maosheng,et al.Decreased NURR1 gene expression in patients with Parkinson's disease[J].J Neurol Sci,2008, 273(1-2): 29-33. 13. Lee B, Cao R, Choi YS,et al.The CREB/CRE transcriptional pathway: protection against oxidative stress-mediated neuronal cell death[J].J Neurochem,2009, 108(5): 1251-1265. |