Migraine is a disabling chronic neurovascular disease characterized by severe hemiplegic headache attacks. Migraine attacks are intensely painful，and when they occur， most activities of daily living and work can no longer be carried out normally，productivity is significantly reduced，and healthcare-related costs are significantly increased. Migraine ranks third among the most common diseases in the world（after dental caries and tension headaches）， and ranks eighth in disability due to disease，with high morbidity，high disease burden，and wide impact. Significant adverse effects on the patient's quality of life.