Acta Neuropharmacologica››2011,Vol. 1››Issue (1): 1-15.
ZHANG Juntian
Online:
2011-02-26Published:
2011-10-20ZHANG Juntian. Neuron-synapse loss and dementias[J]. Acta Neuropharmacologica, 2011, 1(1): 1-15.
1 Holtzman DM. Alzheimer’s disease: Moving towards a vaccine. Nature news,2008,454(Jul,24):418-420 2 Holmes C,Boche D,Wilkinson D,et al.Long-term effects of Aβ42 immunisation in Alzheimer’s disease,placebo-controlled phase l trial [J]. Lancet.2008,372(9634):216-223: follow-up of a randomized 3 Wilcock DM,Gharkholonarehe N,William E. Van Nostrand,et al. Amyloid reduction by amyloid-β vaccination also reduces mouse tau pathology and protects from neuron loss in two mouse models of Alzheimer’s disease[J]. J Neurosci.2009,29(25):7957-7965 4 A. J. Bayer,R. Bullock,R. W. Jones,D. Wilkinson,et al. Evaluation of the safety and immunogenicity of synthetic Aβ42 in patient with AD[J]. Neurology.2005,64(1):94-101 5 徐庆中,卢德宏,董彬,等. Alzheimer’型老年痴呆的神经病理学[M].//盛树力. 老年性痴呆从分子生物学到临床诊治. 北京:科学文献出版社,1998:78-79 6 Selkoe O J. Alzheimer’s disease in a synaptic failure[J]. Science,2000,298(5594):789-791 7 Terry RD. Some morphometric aspects of the brain in senile dementia of the Alzheimer type[J]. Ann Neurol. 1981,10(2):184-192 8 Ball MJ.Neuronal loss ,neurofibrillary tangle and granulo vascular degeneration in the hippocampus with aging brain and senile dementia,A quantitative study[J]. Acta Neuropathol.1977,37(2):111-118 9 Marijke A. M. Lemmens,Annerieke S. R. Sierksma,Bart P. F. Rutten,et al. Age-related changes of neuron numbers in the frontal cortex of a transgenic mouse model of Alzheimer’s disease[DB/OL]. Brain Struct Funct,2011,DOI:10.1007/s00429-011-0305-1 http://www.springerlink.com/content/f6182760623073g6/ 10 Pittman RN. Asynchronous death as a characteristic feature of apoptosis.Cell death and disease of the neurous system[M]// Koliatsos,VE eds. Totowa,Humane Press,1999:29-48 11 Carl W.Cotman,Haoyu Qian,Aileen J. Anderson. Cellular signaling pathways in neuronal apoptosis[M]//Marten E.A.Reith. Cerebral signal transduction. Humana press,2000:175- 206 12 Alvarez VA and Sabatini BL.Anatomical and physiological plasticity of dendritic spines[J]. Annu Rev Neurosci.2007,30:79-97 13 Claudia Ferez-Cruz.Reduced spine density in specific regions of CA1 pyramidal neurons in two transgenic mouse models of Alzheimer’s disease[J]. J Neurosci.2011,31(10):3926-3934 14 Ryan Clare,Victoria G. King,Martin Wirenfeldt,Harry V. Vinters.Synapse loss in dementias[J]. J Neurosci Res.2010,88(10):2083-2090 15 Alvarez VA,Sabatini BL,Annu. Rev. Anatomical and physiological plasticity of dendritic spines[J]. Annu Rev Neurosci.2007,30:79-97 16 Mattson MP. Pathways towards and away from Alzheimer’s disease[J]. Nature. 2004,430(7000):631-639 17 Ming Jin,Nina Shepardson,Ting Yang,et al. Soluble amyloid β-protein dimmers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration[J]. Proc Natl Acad Sci U S A.2011,108(14):5819-5824. 18 Giles E,Hardinham, Hilmar Bading. Synaptic versus extrasynaptic NMDA receptor signaling:implications for neurodegenerative disorders[J],11(10):682-696. Nat Rev Neurosci.2010 19 张均田,郑永芳.细胞内钙和钙通道[M]//韩济生.神经科学原理.上册2版,北京:北京医科大学出版社,1999:222-240 20 Anthony Lau,Michiael Tymianski. Glutamate receptors,Neurotoxicity and neurodegeneration[J]. Eur J Physiol,2010,460(2):525-542. 21 Kelly A. Foster,Nathan McLaughlin,Dieter Edbauer,et al. Distinct roles of NR2A and NR2B cytoplasmic tails in long term potentiation[J]. The journal of neuroscience,2010,30(7):2676-2685 22 Boeckers TM. The postsynaptic density[J]. Cell Tissue Res.2006,326(2):409-422 23 Selkoe DJ.Defining molecular targets to prevent Alzheimer’s disease[J]. Arch Neurol. 2005,62(2):192-195 24 Giles E. Hardingham,Hilmar Bading. Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders[J]. Nat Rev Neurosci.2010,11(10):682-696 25 Gong YS. Lippa CF. Disruption of the postsynaptic density in Alzheimer’s disease and other neurodegenerative dementias[J]. Am J Alzheimers Dis Other Demen.2010,25(7):547-555 26 Sylvain Lesne,Ming Teng Koh,Linda Kotilinek,et al. A specific amyloid-β protein assembly in the brain impairs memory[J]. Nature.2006,440(7082):352-357 27 Yuesong Gong,Lei Chang,Kirsten L. Viola,et al.Alzheimer's disease-affected brain: Presence of oligomeric A(beta) ligands (ADDLs) suggests a molecular basis for reversible memory loss [J]. Proc Natl Acad Sci U S A.2003,100(18):10417-10422 28 Mary P. Lambert,Pauline T. Velasco,Lei Chang,et al. Monoclonal antibodies that target pathological assemblies of Aβ [J] . J Neurochem.2007,100(1):23-35 29 Pascale N. Lacor,Maria C. Buniel,Lei Chang,et al.Synaptic Targeting by Alzheimer’s-Related Amyloid β Oligomers[J]. J Neurosci.2004,24(45):10191-10200 30 Fernanda G. De Felicea,Marcelo N. N. Vieirab,Theresa R. Bomfimb,et al. Protection of synapses against Alzheimer’s-linked toxins: Insulin signaling prevents the pathogenic binding of Aβ oligomers[J]. Proc Natl Acad Sci U S A.2009,106(6):1971-1976 31 Ehud Cohen,Jan Bieschke,Rhonda M. Perciavalle,et al. Opposing activities protect against age-Onset proteotoxicity[J] . Science.2006,313(5793):1604-1610 32 Wtanabe H. Effect of ginseng on spontaneous motor activity ,water maze and dopaminergic in old rats[M]//Shibatas. Recent advances in ginseng studies. Tokyo: Hirokawa Publishing company,1989:73-81 33 Petkov V. Ginseng as a remedy regulating aging processes in brain (Experiment of rats)[M]//Shibata S .Recent advances in ginging studies[M]. Tokyo: Hirokawa Publishing company,1989:83-98 34 Saito H.Effects of ginsenside Rb1 and Rg1 on learning and memory[M]//Shibata S. Recent Advances in Ginseng studies. Tokyo: Hirokawa Publishing company,1989:99-111. 35 Saito H,Tsuchiya M,Naba S,et al. Effects of panax ginseng root on conditioned avoidance respense in rats[J]. Jpn J Pharmacol.1977,27(4):509-516 36 Kennedy D.The effect of ginseng on memory and mood,2002.[M]. Korean society of Ginseng Advances in ginsong research 37 Lawrence C H Wang,Lee T. Effects of ginseng saponins in energy metabolism,memory and anti-neurotoxicity[M]. Korean Society of Ginseng Advances in ginseng research. 2002:27-46 38 Doyle CA, Slater P. Localization of neuronal and endothelial nitric oxide synthase isoforms in human hippocampus[J]. Neuroscience.1997,76(2):387-395 39 Wang X Y,Zhang J T. NO mediates ginsenosideRg1 and Rb1-induced long-term potentiation in anesthetized rats[J]. Acta Pharmacol Sin.2001,22(12):1099-1102 40 Jianfei Xue,Zhijun Liu,Jinfeng Hu,et al. Ginsenoside Rg1 promotes neurotransmitter release by modulating phosphorylation of synapsins through a cAMP-dependent protein kinase pathway[J]. Brain Res.2006,1106(1):91-98 41 杨迎,张均田,石成璋,等. 人参皂甙Rb1和Rg1促智作用机制的探讨──对小鼠脑神经发育的影响[J]. 药学学报.,29(4):241-2451994 42 Higashi H and Chen N. Ganglioside/protein kinase signals triggering cytoskeletal actin reorganization[J]. Glycoconj J.2004,20(1):49-58 43 J.Woodland Hastings and James G. Morin. Photons for reporting molecular events:green fluorescent protein and four luciferase systems[M]//Martin Chalfie and Steven R.Kain. Green fluorescent protein:properties application and protocols. New York: Wiley-liss, 1998:3-15 44 陈乃宏.图像可视化技术在神经药理学研究中的应用[M]//张均田,张庆柱,神经药理学研究技术与方法,北京,人民卫生出版社,2005, 745-757 45 Shen L,Zhang J. Ginsenoside Rg1 increase ischemia-induced cell proliferation and survival in the dentate gyrus of adult gerbils[J]. Neurosci Lett.2003,344(1):1-4 46 申丽红,张均田. 胎鼠神经干细胞培养方法的建立及药物对干细胞增殖的影响[J]. 药学学报.,38(10):735-7382003 47 Shen L H,Zhang J T. Ginsenoside Rg1 promotes proliferation of hippocampal progenitor cells. Neurol Res[J].,26(4):422-4282004 48 Shen L,Zhang J.NMDA receptor and iNOS are involved in the effects of ginsenoside Rg1 on hippocampal neurogenesis in ischemic gerbils[J]. Neurol Res.2007,29(3):270-273 49 Altman J. Autoradiographic and histological studies of postnatal neurogenesis. IV. Cell proliferation and migration in the anterior forebrain,with special reference to persisting neurogenesis in the olfactory bulb[J]. J Comp Neurol.1969,137(4):433-457 50 Altman J,Das G D. Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats[J]. J Comp Neurol.1965,124(3):319-335 51 Eriksson P S,Perfilieva E,Bjork-Eriksson T .Neurogenesis in the adult human hippocampus [J]. Nat Med.1998:4 (11):1313-1317 52Palmer T D,Ray J,Gage F H. FGF-2-responsive neuronal progenitors reside in proliferative and quiescent regions of the adult rodent brain[J]. Mol Cell Neurosci.1995,6(5):474-486 53 Palmer T D,Markakis E A,Willhoite A R,et al. Fibroblast growth factor-2 activates a latent neurogenic program in neural stem cells from diverse regions of the adult CNS[J]. J Neurosci.1999,19(19):8487-8497 54YamaTranscription factor expression and Notch-dependent regulation of neural progenitors in the adult rat spinal cord[J]. J Neurosci.2001,21(24):9814-9823moto S,Naqao M,Suqimori M,et al. 55 Yamada M,Onodera M,Mizuno Y,et al. Neurogenesis in olfactory bulb identified by retroviral labeling in normal and 1-methyl-4-pheny-1,2,3,6-tetrahydropyridine-treated adult mice[J]. Neuroscience.2004,124(1):173-181 56 Belluzzi O,Benedusi M,Ackman J,et al. Electrophysiological differentiation of new neurons in the olfactory bulb[J]. J Neurosci.2003,23(32):10411-10418 57 Carlen M,Cassidy R M, Brismar H, et al. Functional integration of adult- born neurons[J]. Curr Biol.2002,12 (7):606-608 58 Henriette van Praag , Alejandro F. Schinder , Brian R. Christie,et al. Functional neurogenesis in the adult hippocampus[J]. Nature.2002,415(6875):1030-1034. 59 Morshead C M,Van Der Kooy D. Postmitotic death is the fate of constitutively proliferating cells in the subependymal layer of the adult mouse brain[J]. J Neurosci.1992,12(1):249-256 60 Cameron H A,McKay R D. Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus[J]. J Comp Neurol.2001,435(4):406-417 61 Kato T,Yokouchi K, Fukushima N, et al. Continual replacement of newly-generated olfactory neurons in adult rats [J]. Neurosci Lett. 2001,307(1):17-20 62 Kuhn H G,Dickinson-Anson H,Gage F H,Neurogenesis in the dentate gyrus of the adult rat:age-related decrease of neuronal progenitor proliferation[J]. J Neurosci.1996,16(6):2027-2033 63 Shors T J.Miesegaes G,Beylin A,et al. Neurogenesis in the adult is involved in the formation of trace memories[J]. Nature.2001,410(6826):372-276 64 Haughey N J,Liu D,Nath A,et al. Disruption of neurogenesis in the subventricular zone of adult mice,and in human cortical neuronal precursor cells in culture,by amyloid betapeptide: implications for the pathogenesis of Alzheimer’s disease[J]. Neuromolecular Med.2002,1(2):125-135 65 李君庆,张均田.细胞程序性死亡与疾病[J].中国药学杂志 1996,31(4):198-200 66 李君庆,李宇锴,段红,张均田.年龄及人参皂苷 Rg1对大鼠大脑皮层NO释放的影响[J].药学学报,1997,32(4):23-27 67 Li Junqing,Zhang Juntian.Inhibition of apoptosis by ginsenoside Rg1,In cultured cortical neurons[J]. Chin Med J (Engl).1997,110(7):535-539 68 李君庆,张香阁,张均田.人参皂苷Rg1抗神经细胞凋亡作用机制的研究[J].药学学报,1997,32(6):406-410 69 Chen X C,Chen Y,Zhu Y G,et al. Protective effect of ginsenoside Rg1 against MPTP-induced apoptosis in mouse subtantia nigra neurons[J]. Acta Pharmacol Sin. 2002,23(9):829-834 70 Chen X C,Zhu Y G,Wang X Z,et al. Protective effect of ginsenoside Rg1 on dopamine-induced apoptosis in PC12 cells[J]. Acta Pharmacol Sin. 2001,22(8):673-678 |
[1] | ZHANG Xiang-yang.Neurocognitive Impairment in Schizophrenia: Clinical Correlates and Pathophysiological Mechanisms[J]. Acta Neuropharmacologica, 2018, 8(5): 89-90. |
[2] | ZHU Min1, LI Ling-hai2.Advances in Research on Application of Anesthetics and Postoperative Cognitive Dysfunction in Patients[J]. Acta Neuropharmacologica, 2018, 8(3): 32-. |
[3] | WANG Lun-zheng, XIE Wen-juan, TANG Tie-Shan.Neural Stem Cells, Adult Neurogenesis and Cell Therapy for Neurodegenerative Diseases[J]. Acta Neuropharmacologica, 2015, 5(3): 46-64. |
[4] | CHU Shi-feng, ZHANG Jun-tian.A New Type of Anti-dementia Drug: The Chemistry, Biological Activities and Mechanism of Action of (-) Clausenamide[J]. Acta Neuropharmacologica, 2014, 4(6): 33-43. |
[5] | CHEN Jiao, CHU Shi-feng, WANG Zhen-zhen, CHEN Nai-hong.Research Progress of GSK3 in the Pathophysiology of Depression Disorder[J]. Acta Neuropharmacologica, 2014, 4(5): 44-54. |
[6] | WANG Ying, LIU Yu-gang, ZHANG Dan-shen.Animal Models of Alzheimer's Disease: a Review[J]. Acta Neuropharmacologica, 2014, 4(2): 27-38. |
[7] | Tang Min-ke,Fan Yue,Liu Chang-suo,Zhang Jun-tian.Progress of The Mechanisms of Neuroprotective Effects of Salvianolic Acid B[J]. Acta Neuropharmacologica, 2014, 4(1): 1-10. |
[8] | LIU Ting-ting, WANG Wen.Eph/ephrin Signaling Pathway in Brain Neurogenesis[J]. Acta Neuropharmacologica, 2014, 4(1): 25-28. |
[9] | HE Na, YIN Ming, WANG Ze-jian.Progress in the Relationship of Adult Hippocampal Neurogenesis and Alzheime’s Disease[J]. Acta Neuropharmacologica, 2013, 3(6): 25-32. |
[10] | LI Wei,LI Ting-ting,QI Sai-qing,ZHANG Gui-rong.Review on the Impact of Rapid Eye Movement Sleep Deprivation on Synaptic Plasticity and its Molecular Mechanisms[J]. Acta Neuropharmacologica, 2013, 3(4): 47-57. |
[11] | Jin Can, ZHANG Dan-shen, CHEN Nai-hong.Research Advance in Relationship between Adult Hippocampal Neurogenesis and Mechanisms of Depression[J]. Acta Neuropharmacologica, 2013, 3(2): 58-64. |
[12] | ZHANG Xia-wei,ZHANG Dan-shen.Progress in Understanding the Relevance of Learning and Memory to Estrogen and Glu-NMDA Receptor Pathway[J]. Acta Neuropharmacologica, 2011, 1(6): 48-59. |
[13] | CHU Shi-feng, CHEN Nai-hong.Distinct Roles and Modulations of Synaptic and Extrasynaptic NMDA Receptors[J]. Acta Neuropharmacologica, 2011, 1(5): 40-48. |
Viewed | ||||||
Full text |
|
|||||
Abstract |
|
|||||