Acute myocardial infarction （AMI） is the most serious type of cardiovascular disease，which can lead to arrhythmia，heart failure and even sudden death. Recent studies have shown that inflammatory response is closely related to the occurrence and development of AMI and the damage repair after myocardial infarction. As an important part of human immune system，various inflammatory cells are involved in the occurrence and development of AMI. Inflammation-related derived indicators such as NLR，LMR and SII can reflect the inflammatory state of the body，and a large number of studies have found that they have certain predictive value in the diagnosis，treatment，prognosis and complications of AMI. This article mainly reviews the role of inflammation-related derived indicators in AMI，in order to provide a new basis for the pathogenesis and treatment of AMI.