ACTA NEUROPHARMACOLOGICA››2020,Vol. 10››Issue (6): 41-44.DOI:10.3969/j.issn.2095-1396.2020.06.007

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Research Progress of SIRT1 in Cerebral Ischemia-Reperfusion Injury

ZHANG Jia-xiuZOU Yu-an

  1. 1. Graduate School of Hebei North UniversityZhangjiakou075000China

    2. Department of Neurology, the First Affiliated Hospital of Hebei North UniversityZhangjiakou075000China

  • Online:2020-12-26Published:2020-12-26
  • Contact:邹玉安,男,主任医师,硕士研究生导师;E-mail:baiyitiansho@163.com
  • About author:张佳秀,女,欧宝平台登录 研究生学院;研究方向:神经病学;E-mail:zjxiu1993@163.com

Abstract:

Acute ischemic stroke is a kind of disease with complicated pathogenesis and no effective treatment at present. Silencing information regulator 1(SIRT1)is a nicotinamide adenine dinucleotide(NAD+)-dependent deacetylaseand is one of the important regulators of agingapoptosis and other physiological activities. Studies have shown that SIRT1 is closely related to the neuroprotective effect of cerebral ischemia-reperfusion injury and may be a new target for the treatment of acute ischemic stroke.

Key words:

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CLC Number:

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